Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.75 |
| ▸ | IGF1R | P08069 | 7/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | DRD5 | P21918 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307446 | 0.86 | ALOX15 (1.00) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL107170 | 0.86 | ALOX15 (0.90) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL31556198 | 0.84 | ALOX15 (0.95) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL10335381 | 0.84 | ALOX15 (0.95) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL31556196 | 0.84 | ALOX15 (0.95) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL30167965 | 0.84 | ALOX15 (0.95) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL31556189 | 0.84 | ALOX15 (0.95) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL3033234 | 0.83 | ALOX15 (0.52) | ALOX15IGF1RMAPTALOX5TDP1 | |
| SCHEMBL18986571 | 0.82 | ALOX15 (0.50) | ALOX15IGF1RKDM4EMAPTALDH1A1 | |
| SCHEMBL107956 | 0.81 | ALOX15 (0.80) | ALOX15IGF1RKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218377-A | A kind of Hydroxytyrosol NO donor derivative and its preparation method and application | UNIV XI AN JIAOTONG | 2016-01-06 | — | — | CN | claimed |
| CN-105218377-B | A kind of hydroxytyrosol NO donor derivatives and its preparation method and application | 西安交通大学 | 2017-10-27 | — | — | CN | disclosed |
| CN-105218377-A | A kind of Hydroxytyrosol NO donor derivative and its preparation method and application | UNIV XI AN JIAOTONG | 2016-01-06 | — | — | CN | disclosed |