Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005 | 0.97 | ESR1 (0.52) | ESR1THRATHRBSLC6A2TAAR1 | |
| SCHEMBL28040364 | 0.93 | ESR1 (0.48) | ESR1THRATHRBSLC6A2TAAR1 | |
| SCHEMBL12815396 | 0.84 | ESR1 (0.50) | ESR1THRATHRBSLC6A2TAAR1 | |
| SCHEMBL1417168 | 0.83 | ESR1 (0.38) | ESR1SLC6A2TAAR1HTR2ASLC6A4 | |
| SCHEMBL1031401 | 0.78 | ESR1 (0.38) | ESR1SLC6A2TAAR1HTR2ASLC6A4 | |
| SCHEMBL7548637 | 0.78 | SLC6A2 (0.60) | ESR1SLC6A2TAAR1HTR2ASLC6A4 | |
| SCHEMBL6685103 | 0.78 | ESR1 (0.74) | ESR1THRATHRBSLC6A2TAAR1 | |
| SCHEMBL6893902 | 0.76 | ESR1 (0.34) | ESR1SLC6A2TAAR1HTR2ASLC6A4 | |
| SCHEMBL4430003 | 0.75 | MEN1 (0.46) | ESR1SLC6A2TAAR1LMNAESR2 | |
| SCHEMBL3813415 | 0.75 | ESR1 (0.39) | ESR1SLC6A2TAAR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |