Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 8/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005 | 0.80 | ESR1 (0.52) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| Phentermine SCHEMBL28729624 | 0.78 | SLC6A2 (0.95) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL28040853 | 0.78 | ESR1 (0.50) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL1417168 | 0.76 | ESR1 (0.38) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL1031401 | 0.76 | ESR1 (0.38) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| Phentermine SCHEMBL25214698 | 0.76 | SLC6A2 (0.91) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL28040364 | 0.76 | ESR1 (0.48) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL228926 | 0.75 | SLC6A2 (0.67) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| Phentermine SCHEMBL10392295 | 0.75 | SLC6A2 (1.00) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| Phentermine SCHEMBL26615 | 0.75 | SLC6A2 (1.00) | SLC6A2TAAR1HTR2ASLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023312-A | The Compounds and methods for for preventing malarial parasite from propagating | 由卫生与公众服务部部长代表的美利坚合众国 | 2019-07-16 | — | — | CN | claimed |
| CN-1060487-C | Silicone grafted thermoplastic elastomeric copolymers and hair and skin care compositions containing the same | PROCTER & GAMBLE (US) | 2001-01-10 | — | — | CN | claimed |
| CN-1133603-A | Silicone grafted thermoplastic elastomeric copolymers and hair and skin care compositions containing the same | PROCTER & GAMBLE (US) | 1996-10-16 | — | — | CN | claimed |
| CN-110023312-A | The Compounds and methods for for preventing malarial parasite from propagating | 由卫生与公众服务部部长代表的美利坚合众国 | 2019-07-16 | — | — | CN | disclosed |
| US-20020082254-A1 | Compounds for treating disorders where a decreased level of plasma FFA is desired | NOVO NORDISK A/S (DK) | 2002-06-27 | — | — | US | disclosed |
| WO-2001087843-A1 | COMPOUNDS FOR TREATING DISORDERS WHERE A DECREASED LEVEL OF PLASMA FFA IS DESIRED | NOVO NORDISK A/S (DK) | 2001-11-22 | — | — | WO | disclosed |
| EP-0078152-B1 | SALTS OF SULFODEHYDROABIETIC ACID AND TREATMENT OF GASTRO-INTESTINAL DISEASES | Tanabe Seiyaku Co., Ltd. (JP) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082254-A1 | Compounds for treating disorders where a decreased level of plasma FFA is desired | FABP1, FFAR2, FFAR1 | SLC6A2 1103/4885TAAR1 1819/4885HTR2A 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.