SCHEMBL28040929

SCHEMBL28040929

CCOC(OCC)C(N)([SiH3])CC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441768 0.74 THRB (0.38) THRBLMNA
SCHEMBL442787 0.70 THRB (0.40) THRBLMNA
SCHEMBL25688960 0.69 THRB (0.38) THRBLMNA
SCHEMBL1819411 0.68 THRB (0.33) THRBLMNA
SCHEMBL28001860 0.67 THRB (0.32) THRBLMNA
SCHEMBL4119768 0.67 THRB (0.36) THRBLMNA
SCHEMBL27995740 0.65 THRB (0.31) THRB
SCHEMBL11784936 0.65
SCHEMBL14484876 0.65 THRB (0.40) THRBLMNA
SCHEMBL6970379 0.64 MEN1 (0.35) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102405224-B Comprise composition and the Synthesis and applications thereof of season amino-functional silicoorganic compound EVONIK DEGUSSA GMBH (DE) 2015-12-16 CN claimed
CN-102405224-B Comprise composition and the Synthesis and applications thereof of season amino-functional silicoorganic compound EVONIK DEGUSSA GMBH (DE) 2015-12-16 CN disclosed
CN-102405251-B Based on the aqueous silane system and uses thereof of three (alkoxysilylalkyl) amine EVONIK DEGUSSA GMBH (DE) 2015-11-25 CN disclosed