SCHEMBL28041002

SCHEMBL28041002

CCCCCCCCCCCCSC(CC(=O)c1ccc(-c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HPGD P15428 2/20 0.48
MAPT P10636 3/20 0.47
POLB P06746 1/20 0.42
CYP1A2 P05177 1/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
AGTR1 P30556 1/20 0.42
HDAC1 Q13547 2/20 0.41
GAA P10253 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
RARB P10826 4/20 0.41
MEN1 O00255 1/20 0.41
RARA P10276 1/20 0.41
MTOR P42345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14602841 0.92 PDPK1 (0.51) PDPK1MEN1KMT2ASOAT2ACAT1
SCHEMBL28937529 0.92 PDPK1 (0.51) PDPK1MEN1KMT2ASOAT2ACAT1
SCHEMBL14602856 0.92 PDPK1 (0.51) PDPK1MEN1KMT2ASOAT2ACAT1
SCHEMBL28041003 0.83 SOAT1 (0.41) PDPK1SMN1; SMN2MAPTCYP1A2KDM4E
SCHEMBL9109873 0.83 CYSLTR2 (0.47) SOAT2ACAT1SOAT1
SCHEMBL9109323 0.83 CYSLTR2 (0.47) SOAT2ACAT1SOAT1
SCHEMBL23531267 0.78 PDPK1 (0.61) PDPK1SMN1; SMN2L3MBTL1HPGDMAPT
SCHEMBL18737489 0.74 SMN1; SMN2 (0.57) SMN1; SMN2L3MBTL1HPGDMAPTPOLB
SCHEMBL909083 0.74 PDPK1 (0.57) PDPK1SMN1; SMN2L3MBTL1HPGDMAPT
SCHEMBL13670588 0.73 L3MBTL1 (0.74) SMN1; SMN2L3MBTL1HPGDMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085339-A Synthetic method for 1-p-biphenylyl-3-phenyl-3-(dodecylthio) propane-1-one ANHUI SHIHUA CHEMICAL CO LTD 2015-11-25 CN disclosed
CN-105085339-A Synthetic method for 1-p-biphenylyl-3-phenyl-3-(dodecylthio) propane-1-one ANHUI SHIHUA CHEMICAL CO LTD 2015-11-25 CN disclosed