SCHEMBL2804117

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2808549	0.92	AXL (0.44)	SIGMAR1PLK1IGF1RKCNH2DRD2
	SCHEMBL2802601	0.91	SIGMAR1 (0.47)	SIGMAR1PLK1ALDH1A1TP53CYP1A2
	SCHEMBL2805415	0.90	SIGMAR1 (0.46)	SIGMAR1DRD2ALDH1A1TP53CYP1A2
	SCHEMBL2801907	0.89	PLK1 (0.44)	SIGMAR1PLK1IGF1RDRD2DRD4
	SCHEMBL2804912	0.89	CHKA (0.41)	SIGMAR1OPRL1
	SCHEMBL2805196	0.89	SIGMAR1 (0.50)	SIGMAR1POLBDRD2ALDH1A1TP53
	SCHEMBL2803730	0.88	SIGMAR1 (0.45)	SIGMAR1DRD2ALDH1A1TP53CYP1A2
	SCHEMBL2804751	0.86	SIGMAR1 (0.40)	SIGMAR1PLK1IGF1RALDH1A1
	SCHEMBL2803126	0.86	SIGMAR1 (0.53)	SIGMAR1PLK1SMN1; SMN2IGF1RDRD2
	SCHEMBL2807860	0.86	TP53 (0.38)	SIGMAR1PLK1SMN1; SMN2IGF1RKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.