Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418739 | 0.83 | HSD17B10 (0.45) | ADRA1ATAAR1HTR2AIDO1ADRA2A | |
| SCHEMBL7414770 | 0.83 | HTR2A (0.49) | ADRA1ATAAR1HTR2AIDO1AOC3 | |
| SCHEMBL42578 | 0.82 | ADRA1A (0.72) | ADRA1ATAAR1HTR2AIDO1ADRA2A | |
| SCHEMBL27913813 | 0.81 | ADRA1A (0.49) | ADRA1ATAAR1HTR2AIDO1ADRA2A | |
| SCHEMBL15716061 | 0.78 | BACE1 (0.39) | MEN1KMT2APOLB | |
| SCHEMBL16756452 | 0.77 | SLC6A2 (0.39) | IDO1 | |
| SCHEMBL27932793 | 0.77 | MAPT (0.63) | ADRA1ATAAR1HTR2AIDO1ADRA2A | |
| SCHEMBL15539889 | 0.76 | KMT2A (0.46) | HTR2AHTR2BHSD17B10MEN1MAPT | |
| SCHEMBL16953984 | 0.75 | MAPT (0.48) | ADRA1AHTR2AADRA2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL15559545 | 0.75 | KMT2A (0.45) | HTR2AIDO1HTR2BHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995176-A | Hydantoins that modulate BACE mediated APP processing | BUCK INST FOR RES ON AGING | 2015-10-21 | — | — | CN | disclosed |