SCHEMBL28041263

SCHEMBL28041263

COC(=O)C(c1ccccc1)c1ccc(O)cc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.55
KMT2A Q03164 4/20 0.49
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
PDK2 Q15119 1/20 0.42
PDK4 Q16654 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
MEN1 O00255 3/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27469447 0.84 KMT2A (0.55) KMT2ACNR1CNR2PTGS1PTGS2
SCHEMBL27965885 0.82 TYR (0.59) TYRKMT2ACA12CA1CA2
SCHEMBL3453799 0.82 TYR (0.59) TYRKMT2ACA12CA1CA2
SCHEMBL13749034 0.81 ESR1 (0.46) KMT2ACNR1CNR2MEN1GAA
Potassium SCHEMBL9061207 0.81 TYR (0.57) TYRKMT2ACA12CA1CA2
SCHEMBL2843638 0.80 KMT2A (0.58) KMT2ACNR1CNR2
SCHEMBL22839889 0.80 KMT2A (0.53) KMT2APTGS1PTGS2MEN1KDM4E
Methane SCHEMBL28696266 0.79 KMT2A (0.56) KMT2ACNR1CNR2
SCHEMBL1578804 0.78 KMT2A (0.69) KMT2APTGS1PTGS2
SCHEMBL27965897 0.78 KMT2A (0.52) KMT2ACNR1CNR2PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103936537-B A kind of phenol of golden catalysis and the selectivity c h bond functionalization method of aniline EAST CHINA NORMAL UNIVERSITY (CN) 2015-10-28 CN disclosed