SCHEMBL3453799

SCHEMBL3453799

O=C(C(c1ccccc1)c1ccc(O)cc1O)C(c1ccccc1)c1ccc(O)cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.59
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.43
KMT2A Q03164 2/20 0.43
USP2 O75604 1/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
ALOX5 P09917 1/20 0.41
CA12 O43570 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL9061207 0.98 TYR (0.57) TYRMEN1GAAKMT2AUSP2
SCHEMBL27965885 0.89 TYR (0.59) TYRMEN1GAAKMT2AUSP2
SCHEMBL9061952 0.86 TYR (0.46) TYRMEN1GAAKMT2AUSP2
SCHEMBL27629361 0.83 LMNA (0.46) TYRHDAC3HDAC4HDAC1HDAC7
SCHEMBL31413333 0.83 KMT2A (0.57) TYRMEN1GAAKMT2ACNR1
SCHEMBL31413334 0.83 TYR (0.47) TYRMEN1KMT2ACNR1CNR2
SCHEMBL11558507 0.82 HPGD (0.50) TYRMEN1KMT2ACNR1CNR2
SCHEMBL28041263 0.82 TYR (0.55) TYRMEN1GAAKMT2ACNR1
SCHEMBL11833120 0.81 TYR (0.46) TYRMEN1GAAKMT2ACNR2
SCHEMBL8983949 0.81 TYR (0.46) TYRMEN1GAAKMT2ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112888498-B Composition useful for making acid gas separation membranes 住友化学株式会社 2023-07-14 CN claimed
EP-2114847-B1 METHOD FOR THE PRODUCTION OF 2,4-DIHYDROXYPHENYL-BENZYL KETONES PLANT HEALTH CARE INC (US) 2017-03-22 EP claimed
EP-0941992-B1 Ipriflavone preparation process ERREGIERRE SPA (IT) 2002-05-08 EP claimed
US-5973169-A Ipriflavone preparation process ERREGIERRE S.P.A. (IT) 1999-10-26 US claimed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP claimed
JP-9157268-A None JP disclosed
JP-60048924-A None JP disclosed
CN-112888498-B Composition useful for making acid gas separation membranes 住友化学株式会社 2023-07-14 CN disclosed
CN-112888498-A Composition useful for producing acid gas separation membranes 住友化学株式会社 2021-06-01 CN disclosed
US-7820836-B2 Process for the manufacture of hydroxylated isoflavones DSM IP ASSETS B.V. (NL) 2010-10-26 US disclosed
US-20090287001-A1 Process for the Manufacture of Hydroxylated Isoflavones DSM IP ASSETS B.V. (NL) 2009-11-19 US disclosed
EP-1542675-A4 COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH ENDOWMENT FOR RES IN HUMAN BIO (US) 2008-11-19 EP disclosed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP disclosed
JP-H09157268-A PRODUCTION OF 7-HYDROXYISOFLAVONE AND ITS PURIFICATION NIPPON KAYAKU CO LTD 1997-06-17 JP disclosed
EP-0478559-B1 IMPROVED PROCESS FOR THE PREPARATION OF KETONE COMPOUNDS CHINOIN GYOGYSZER ES VEGYESZET (HU) 1996-01-31 EP disclosed
EP-0478558-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED ISOFLAVONE DERIVATIVES CHINOIN GYOGYSZER ES VEGYESZET (HU) 1994-02-02 EP disclosed
US-5247102-A Cyclization of a resorcinol derivative with ethyl orthoformate in the presence of a base CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1993-09-21 US disclosed
US-5235109-A Reacting a phenol with anhydrous aluminum chloride to form a complex, acylating, separation CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT (HU) 1993-08-10 US disclosed
JP-S6048924-A REMEDY FOR OSTEOPOROSIS TAKEDA CHEM IND LTD 1985-03-16 JP disclosed
US-4163746-A ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287001-A1 Process for the Manufacture of Hydroxylated Isoflavones EGLN2, PAH, EGLN3 TYR 81/4885MEN1 2327/4885GAA 1824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.