Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946164 | 0.88 | ALDH1A1 (0.38) | ALDH1A1TDP1HPGDKMT2ATSHR | |
| SCHEMBL6658253 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1F2RL3HPGDKMT2A | |
| SCHEMBL27928233 | 0.83 | HPGD (0.40) | NPC1KDM4EBRD4MITFL3MBTL1 | |
| SCHEMBL28041426 | 0.82 | HPGD (0.43) | NPC1KDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL26462910 | 0.81 | TDP1 (0.40) | KDM4EL3MBTL1ALDH1A1TDP1HPGD | |
| SCHEMBL3781650 | 0.81 | TDP1 (0.45) | ALDH1A1TDP1KMT2APOLBTSHR | |
| SCHEMBL3818387 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1HPGDTSHRS100A4 | |
| SCHEMBL16961033 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRS100A4GPR35 | |
| SCHEMBL16154022 | 0.79 | RECQL (0.41) | NPC1L3MBTL1ALDH1A1HPGDKMT2A | |
| SCHEMBL27928234 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1HPGDPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415510-B | The preparation method of aminophenyl pyrimidyl alcohol derivate and synthetic intermediate thereof | IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) | 2016-01-13 | — | — | CN | disclosed |