SCHEMBL28041588

SCHEMBL28041588

COCO[C@@H](C)C(NC(=O)O)c1ccccc1F

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
PPARG P37231 1/20 0.37
CYP3A4 P08684 1/20 0.36
CTSA P10619 8/20 0.36
MC4R P32245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041541 0.85 KDM4E (0.36) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL28041534 0.85 MEN1 (0.45) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL28041751 0.85 GAA (0.40) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL28041525 0.84 CTSA (0.39) MEN1KMT2AALDH1A1CTSA
SCHEMBL16054881 0.77 GAA (0.46) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL28990587 0.76 GAA (0.43) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL27865091 0.75 CNR2 (0.40) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL16067608 0.74 CYP3A4 (0.36) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL28990511 0.74 CYP3A4 (0.36) CNR2MEN1KMT2AGAAALDH1A1
SCHEMBL15080167 0.73 MEN1 (0.38) CNR2MEN1KMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111419830-B Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes 比皮艾思药物研发有限公司 2024-01-30 CN disclosed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN disclosed
CN-111419830-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes 比皮艾思药物研发有限公司 2020-07-17 CN disclosed
CN-105209027-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes BIO PHARM SOLUTIONS CO LTD 2015-12-30 CN disclosed