Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 11/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041541 | 0.85 | KDM4E (0.36) | MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL15067314 | 0.85 | POLB (0.41) | CTSACASP1ADRB2ADRB1MEN1 | |
| SCHEMBL28041744 | 0.85 | CASP1 (0.40) | CTSACASP1MEN1KMT2AOPRM1 | |
| SCHEMBL28041588 | 0.84 | CNR2 (0.41) | CTSAMEN1KMT2AALDH1A1 | |
| SCHEMBL28478888 | 0.78 | LPAR1 (0.41) | CTSACASP1ADRB2ADRB1MEN1 | |
| SCHEMBL28990607 | 0.78 | LPAR1 (0.41) | CTSACASP1ADRB2ADRB1MEN1 | |
| SCHEMBL11244690 | 0.78 | CXCL8 (0.44) | CTSACASP1ADRB2ADRB1MEN1 | |
| SCHEMBL15067442 | 0.77 | ADRB2 (0.45) | CTSACASP1ADRB2ADRB1CXCL8 | |
| SCHEMBL15067585 | 0.77 | ADRB2 (0.45) | CTSACASP1ADRB2ADRB1CXCL8 | |
| SCHEMBL15067895 | 0.77 | ADRB2 (0.45) | CTSACASP1ADRB2ADRB1CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-111419830-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | 比皮艾思药物研发有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |