Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.71 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041853 | 0.87 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL28041633 | 0.84 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL16211574 | 0.83 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL28041630 | 0.80 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL28824002 | 0.79 | CNR2 (0.72) | CNR2CNR1YTHDC1 | |
| SCHEMBL28214711 | 0.78 | YTHDC1 (0.47) | CNR2CNR1YTHDC1 | |
| SCHEMBL28041634 | 0.76 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL16211953 | 0.73 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL16212012 | 0.71 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL16211993 | 0.71 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209466-B | purine derivatives as CB2 receptor agonists | 豪夫迈·罗氏有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-105209466-A | Purine derivatives as cb2 receptor agonists | HOFFMANN LA ROCHE | 2015-12-30 | — | — | CN | claimed |
| CN-105209466-B | purine derivatives as CB2 receptor agonists | 豪夫迈·罗氏有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-105209466-A | Purine derivatives as cb2 receptor agonists | HOFFMANN LA ROCHE | 2015-12-30 | — | — | CN | disclosed |