Biphenyl

Biphenyl

SCHEMBL28042001

Nc1ccccc1C(=O)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.88
GAA P10253 1/20 0.88
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA9 Q16790 1/20 0.63
CDC25B P30305 1/20 0.58
ATM Q13315 1/20 0.58
POLB P06746 1/20 0.58
AKR1C3 P42330 1/20 0.55
ADORA1 P30542 1/20 0.53
MAPK14 Q16539 2/20 0.51
MAPK13 O15264 1/20 0.51
MAPK12 P53778 1/20 0.51
MAPK11 Q15759 1/20 0.51
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
USP2 O75604 1/20 0.50
GLA P06280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11772622 0.94 MAPT (0.78) MAPTGAACA1CA2CA9
SCHEMBL28746 0.94 MAPT (1.00) MAPTGAACA1CA2CA9
SCHEMBL29602136 0.94 MAPT (1.00) MAPTGAACA1CA2CA9
Benzophenone SCHEMBL15661696 0.92 MAPT (0.96) MAPTGAACA1CA2CA9
SCHEMBL7612010 0.92 MAPT (0.96) MAPTGAACA1CA2CA9
SCHEMBL31333067 0.92 MAPT (0.96) MAPTGAACA1CA2CA9
SCHEMBL7612003 0.92 MAPT (0.96) MAPTGAACA1CA2CA9
SCHEMBL3138398 0.90 MAPT (0.77) MAPTGAACA1CA2CA9
Nitrogen SCHEMBL28332724 0.90 MAPT (0.92) MAPTGAACA1CA2CA9
SCHEMBL5361720 0.89 MAPT (0.70) MAPTGAACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105121478-A Modified conjugated diene polymer, method for producing same, and rubber composition using same UBE INDUSTRIES 2015-12-02 CN disclosed
CN-105121477-A Catalyst for polymerization of conjugated diene, conjugated diene polymer using the catalyst, modified conjugated diene polymer, process for production of the polymer, rubber composition for tire, and rubber composition for rubber belt UBE INDUSTRIES 2015-12-02 CN disclosed