SCHEMBL29602136

SCHEMBL29602136

Nc1ccccc1C(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 1.00
GAA P10253 1/20 1.00
POLB P06746 1/20 0.63
AKR1C3 P42330 1/20 0.61
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
ALDH1A1 P00352 3/20 0.56
HSD17B10 Q99714 3/20 0.55
LMNA P02545 2/20 0.55
MEN1 O00255 1/20 0.55
USP2 O75604 1/20 0.55
GLA P06280 1/20 0.55
KMT2A Q03164 1/20 0.55
TSHR P16473 1/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
PBRM1 Q86U86 1/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28746 1.00 MAPT (1.00) MAPTGAAPOLBAKR1C3CA1
SCHEMBL7612003 0.98 MAPT (0.96) MAPTGAAPOLBAKR1C3CA1
SCHEMBL7612010 0.98 MAPT (0.96) MAPTGAAPOLBAKR1C3CA1
Benzophenone SCHEMBL15661696 0.98 MAPT (0.96) MAPTGAAPOLBAKR1C3CA1
SCHEMBL31333067 0.98 MAPT (0.96) MAPTGAAPOLBAKR1C3CA1
Nitrogen SCHEMBL28332724 0.96 MAPT (0.92) MAPTGAAPOLBAKR1C3CA1
Biphenyl SCHEMBL28042001 0.94 MAPT (0.88) MAPTGAAPOLBAKR1C3CA1
Acetic Acid SCHEMBL6211199 0.94 MAPT (0.88) MAPTGAAPOLBAKR1C3CA1
SCHEMBL8374908 0.93 MAPT (0.87) MAPTGAAPOLBAKR1C3CA1
Trimethylammonium SCHEMBL27837120 0.92 MAPT (0.85) MAPTGAAPOLBAKR1C3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118598854-A Small molecular compound with high HPPD (high-pressure sensitive PD) inhibitory activity and synthesis method thereof 上海冰鉴信息科技有限公司 2024-09-06 CN claimed
EP-4370498-A1 MULTIFUNCTIONAL CROSSLINKERS: COMPOUNDS, COMPOSITIONS, AND PRODUCTS THEREOF Biocoat, Incorporated (US) 2024-05-22 EP claimed
WO-2023287638-A1 MULTIFUNCTIONAL CROSSLINKERS: COMPOUNDS, COMPOSITIONS, AND PRODUCTS THEREOF BIOCOAT, INCORPORATED (US) 2023-01-19 WO claimed
WO-2026086794-A1 ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-04-30 WO disclosed
CN-115209883-B Novel cell metabolism regulating compound and use thereof 新月生物科学 2025-05-20 CN disclosed
EP-4529621-A1 UV/HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 EP disclosed
US-20250099407-A1 2-AMINO BENZOPHENONE DERIVATIVES FOR TARGETED FERROPTOSIS INDUCTION IN CANCER THERAPY INDIAN INSTITUTE OF TECHNOLOGY KANPUR (IN) 2025-03-27 US disclosed
US-20250099407-A1 2-AMINO BENZOPHENONE DERIVATIVES FOR TARGETED FERROPTOSIS INDUCTION IN CANCER THERAPY INDIAN INSTITUTE OF TECHNOLOGY KANPUR (IN) 2025-03-27 US disclosed
CN-119322428-A Preparation method of photosensitive nano-particles, photoresist solution and two-photon pattern 甬江实验室 2025-01-17 CN disclosed
CN-119072467-A Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof 巴鲁克斯布伦博格研究所 2024-12-03 CN disclosed
CN-118598854-A Small molecular compound with high HPPD (high-pressure sensitive PD) inhibitory activity and synthesis method thereof 上海冰鉴信息科技有限公司 2024-09-06 CN disclosed
CN-113501764-B Asymmetric synthesis method of trifluoromethyl-containing polyfunctional cyclopentenone derivative 重庆大学 2023-05-23 CN disclosed
CN-113501766-B Asymmetric synthesis method of multi-functional cyclopentenone derivative containing difluoroalkyl 重庆大学 2023-05-23 CN disclosed
EP-4093384-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF Crescenta Biosciences (US) 2022-11-30 EP disclosed
CN-115209883-A Novel cell metabolism-regulating compounds and uses thereof 新月生物科学 2022-10-18 CN disclosed
CN-114736131-A Synthetic method of bromfenac sodium 郑州灏瑞医药科技有限公司 2022-07-12 CN disclosed
US-11359123-B2 Compositions containing difluoromethane, tetrafluoropropene, and carbon dioxide and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2022-06-14 US disclosed
WO-2022102407-A1 PHOSPHOR 住友化学株式会社 2022-05-19 WO disclosed
WO-2022102409-A1 PHOSPHOR 住友化学株式会社 2022-05-19 WO disclosed
WO-2022102408-A1 PHOSPHOR 住友化学株式会社 2022-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099407-A1 2-AMINO BENZOPHENONE DERIVATIVES FOR TARGETED FERROPTOSIS INDUCTION IN CANCER THERAPY AIFM2, BAD, MCL1 MAPT 3272/4885GAA 2983/4885POLB 4548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.