Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520581 | 0.80 | MAPT (0.49) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL519468 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL17611061 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL30020977 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL522109 | 0.75 | KMT2A (0.48) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL18689666 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL29943719 | 0.72 | EPHX1 (0.50) | ALDH1A1KMT2AKDM4EMEN1ALOX12 | |
| SCHEMBL19222024 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL31398632 | 0.70 | ALDH1A1 (0.77) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL24747452 | 0.68 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130992-A | Nitrogen-containing heterocyclic compound having kinase inhibiting activity, preparation method and application | UNIV SOOCHOW | 2015-12-09 | — | — | CN | disclosed |