Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.46 |
| ▸ | PDE4A | P27815 | 9/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL15194106 | 1.00 | LMNA (0.46) | LMNAPDE4BPDE4APDE4CPDE4D | |
| D-Leucine SCHEMBL15300397 | 1.00 | LMNA (0.46) | LMNAPDE4BPDE4APDE4CPDE4D | |
| Valine SCHEMBL19097377 | 0.90 | LMNA (0.47) | LMNAPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15198848 | 0.89 | LMNA (0.56) | LMNAPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15198849 | 0.89 | LMNA (0.56) | LMNAPDE4BPDE4APDE4CPDE4D | |
| Leucine SCHEMBL18074074 | 0.86 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DHTR2B | |
| Leucine SCHEMBL18074075 | 0.86 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DHTR2B | |
| Levacetylleucine SCHEMBL756572 | 0.84 | LMNA (0.45) | LMNAPDE4BPDE4APDE4CPDE4D | |
| Levacetylleucine SCHEMBL7084218 | 0.84 | LMNA (0.45) | LMNAPDE4BPDE4APDE4CPDE4D | |
| Levacetylleucine SCHEMBL21229236 | 0.84 | LMNA (0.45) | LMNAPDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105004693-A | Tablets containing Apremilast active ingredients and vitro dissolution determination method thereof | NANJING HEALTHNICE MEDICAL TECHNOLOGY CO LTD | 2015-10-28 | — | — | CN | disclosed |