Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105491 | 0.82 | TSHR (0.75) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| Phosphine SCHEMBL28496548 | 0.81 | TSHR (0.72) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| Phosphine SCHEMBL28493400 | 0.81 | TSHR (0.72) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| SCHEMBL1752774 | 0.80 | MAPK1 (0.64) | SMN1; SMN2MAPK1TSHRRAF1EGFR | |
| SCHEMBL25439893 | 0.80 | TSHR (0.64) | SMN1; SMN2MAPK1TSHREGFRKDM4E | |
| SCHEMBL28931930 | 0.79 | EGFR (0.73) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| SCHEMBL28495999 | 0.79 | EGFR (0.73) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| Trimethylammonium SCHEMBL27715481 | 0.78 | TSHR (0.67) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| SCHEMBL27708108 | 0.78 | EGFR (0.71) | SMN1; SMN2TSHREGFRKDM4EPTPN1 | |
| SCHEMBL28042193 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2ALOX15KDM4ELMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130916-A | Method for efficiently preparing NH-1,2,3 triazole compound | UNIV JIANGXI NORMAL | 2015-12-09 | — | — | CN | disclosed |