SCHEMBL28042398

SCHEMBL28042398

c1ccc2c(c1)Cc1c(-c3ccncc3)cccc1-2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.54
CDK2 P24941 1/20 0.54
PNMT P11086 1/20 0.47
CYP19A1 P11511 3/20 0.41
TNF P01375 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MAOA P21397 1/20 0.41
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
NOTUM Q6P988 1/20 0.40
KDR P35968 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28891159 0.86 CDK1 (0.49) CDK1CDK2PNMTCYP19A1TNF
SCHEMBL29809707 0.84 PNMT (0.53) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL70992 0.84 PNMT (0.53) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL29401802 0.84 PNMT (0.53) PNMTNPC1RAB9AKDRADORA2A
Bromide SCHEMBL15404509 0.82 PNMT (0.52) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL27718430 0.82 PNMT (0.52) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL524602 0.82 PNMT (0.63) PNMTNPC1RAB9AMAOADRD2
SCHEMBL30103334 0.82 PNMT (0.63) PNMTNPC1RAB9AMAOADRD2
SCHEMBL28928665 0.81 PNMT (0.50) PNMTNPC1RAB9AKDRADORA2A
Water SCHEMBL27894037 0.81 PNMT (0.50) PNMTNPC1RAB9AKDRADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017292-A Fluorescence probe for quickly recognizing methanol molecules and application thereof XIONG LILI 2015-11-04 CN claimed
CN-105017292-A Fluorescence probe for quickly recognizing methanol molecules and application thereof XIONG LILI 2015-11-04 CN disclosed