Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316987 | 0.92 | TAAR1 (0.57) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL28311259 | 0.90 | TAAR1 (0.55) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL28042450 | 0.77 | BCL2L1 (0.37) | CYP11B1CYP11B2PTPN1 | |
| SCHEMBL19471215 | 0.77 | ALDH1A1 (0.47) | TAAR1ESR2CYP3A4NOTUMKDM4E | |
| SCHEMBL11973522 | 0.76 | MEN1 (0.48) | TAAR1ESR2CYP3A4NISCHHSD17B1 | |
| SCHEMBL198702 | 0.76 | TAAR1 (0.68) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| Biphenyl SCHEMBL25183774 | 0.74 | TAAR1 (0.67) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL29451178 | 0.74 | TAAR1 (0.67) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL200605 | 0.74 | TAAR1 (0.67) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL16605626 | 0.73 | TAAR1 (0.65) | TAAR1ESR2CYP17A1CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105101967-A | Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof | ABT HOLDING CO | 2015-11-25 | — | — | CN | disclosed |