Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21678908 | 1.00 | LMNA (0.50) | LMNAPLGPLATTSHRGABRP | |
| Cyclopropane Carboxylic Acid SCHEMBL630476 | 0.83 | LMNA (0.59) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL467970 | 0.83 | — | — | |
| Hydrazine SCHEMBL25308605 | 0.80 | LMNA (0.62) | LMNAPLGPLATTSHRGABRP | |
| Cyclopropane Carboxylic Acid SCHEMBL15610129 | 0.80 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.80 | — | — | |
| SCHEMBL329128 | 0.80 | TSHR (0.61) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL36093 | 0.80 | TSHR (0.61) | LMNAPLGPLATTSHRGABRP | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.80 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102884065-B | Heteroaryl-cyclohexyl-tetraazabenzo [ e ] azulenes | HOFFMAN-LA ROCHE LTD. (CH) | 2015-11-25 | — | — | CN | disclosed |