Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27160251 | 1.00 | HSD17B10 (0.40) | HSD17B10CASP3DPP4HRH3HPGD | |
| SCHEMBL31016714 | 0.79 | HSD17B10 (0.42) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL12084380 | 0.79 | HSD17B10 (0.42) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL14938657 | 0.79 | CASP3 (0.43) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL7362291 | 0.79 | HSD17B10 (0.42) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL2677782 | 0.79 | HSD17B10 (0.42) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL8490471 | 0.79 | HSD17B10 (0.42) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL23999544 | 0.77 | HSD17B10 (0.41) | HSD17B10CASP3DPP4HRH3HPGD | |
| SCHEMBL10211022 | 0.77 | HSD17B10 (0.41) | HSD17B10CASP3HRH3HPGDROCK2 | |
| SCHEMBL3898404 | 0.77 | HSD17B10 (0.41) | HSD17B10CASP3DPP4HRH3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240611-A1 | METHODS FOR PREPARING DPP-IV INHIBITOR COMPOUNDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-09-23 | — | — | US | disclosed |
| WO-2010107809-A2 | METHODS FOR PREPARING DPP-IV INHIBITOR COMPOUNDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240611-A1 | METHODS FOR PREPARING DPP-IV INHIBITOR COMPOUNDS | DPP4, DPP3, DPP7 | HSD17B10 853/4885CASP3 860/4885DPP4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.