Toluene

Toluene

SCHEMBL28042841

CCCCCN(CCCCC)Cc1c[nH]nn1.Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 9/20 0.38
MCHR1 Q99705 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
BCHE P06276 2/20 0.34
DRD2 P14416 2/20 0.34
OPRM1 P35372 2/20 0.34
DRD3 P35462 2/20 0.34
OPRD1 P41143 2/20 0.34
OPRK1 P41145 2/20 0.34
ICMT O60725 1/20 0.34
ALB P02768 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28043018 0.99 KCNH2 (0.40) KCNH2MCHR1MEN1KMT2ANPSR1
Toluene SCHEMBL28043021 0.99 KCNH2 (0.40) KCNH2MCHR1MEN1KMT2ANPSR1
Toluene SCHEMBL28824393 0.90 TSHR (0.35) KCNH2MEN1KMT2ABCHEDRD3
SCHEMBL29661945 0.87 KCNH2 (0.35) KCNH2MCHR1BCHE
SCHEMBL29661978 0.87 KCNH2 (0.35) KCNH2MCHR1BCHE
SCHEMBL29661907 0.87 KCNH2 (0.35) KCNH2MCHR1BCHE
SCHEMBL29661929 0.87 KCNH2 (0.35) KCNH2MCHR1BCHE
SCHEMBL29661983 0.87 KCNH2 (0.35) KCNH2MCHR1BCHE
SCHEMBL10600926 0.84 KCNH2 (0.35) KCNH2MCHR1
SCHEMBL10600535 0.84 KCNH2 (0.35) KCNH2MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103589486-B Refrigerator oil and working fluid composition for refrigerating machine 捷客斯能源株式会社 2016-08-17 CN disclosed
CN-105567397-A Refrigerating machine oil and working fliud composition for refrigerating machine JX NIPPON OIL & ENERGY CORP 2016-05-11 CN disclosed
CN-102482611-B Refrigerator oil and working fluid composition for refrigerator JX NIPPON OIL & ENERGY CORP. (JP) 2016-01-20 CN disclosed