Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286771 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL7095588 | 0.95 | MAPT (0.55) | MAPTNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL1259708 | 0.83 | — | — | |
| SCHEMBL1259696 | 0.83 | — | — | |
| SCHEMBL27617928 | 0.81 | MAPT (0.59) | MAPTNPC1RAB9AALDH1A1CYP1A2 | |
| Morpholine SCHEMBL27881990 | 0.80 | CHRNA4 (0.44) | MAPTNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL6980382 | 0.79 | PKM (0.58) | MAPTNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL345038 | 0.78 | MAPT (0.67) | MAPTNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL16908080 | 0.77 | — | — | |
| SCHEMBL1189897 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105232817-A | Medicinal composition for treating physiological disorder, and preparation method thereof | UNIV XINXIANG MEDICAL | 2016-01-13 | — | — | CN | disclosed |