Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15461606 | 0.77 | SLC6A2 (0.33) | — | |
| SCHEMBL4849500 | 0.77 | MAOB (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL15946040 | 0.75 | SLC6A2 (0.32) | — | |
| SCHEMBL15946041 | 0.75 | SLC6A2 (0.32) | — | |
| SCHEMBL15576237 | 0.75 | SLC6A2 (0.32) | — | |
| SCHEMBL27836357 | 0.74 | HMGCR (0.32) | HMGCR | |
| SCHEMBL4161502 | 0.73 | HMGCR (0.42) | HMGCR | |
| SCHEMBL4185693 | 0.73 | HMGCR (0.42) | HMGCR | |
| SCHEMBL4161500 | 0.73 | HMGCR (0.42) | HMGCR | |
| SCHEMBL4185690 | 0.73 | HMGCR (0.42) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |