SCHEMBL28043044

SCHEMBL28043044

CCC(N)C(=O)Nc1cccc(F)c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 2/20 0.49
PLK3 Q9H4B4 1/20 0.49
HDAC2 Q92769 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
PTPN1 P18031 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
POLB P06746 1/20 0.39
KCNQ2 O43526 1/20 0.39
CTSC P53634 1/20 0.39
ITGB2 P05107 1/20 0.38
ICAM1 P05362 1/20 0.38
ITGAL P20701 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19209037 0.86 GAA (0.44) PLK1PLK3HDAC2ALDH1A1GAA
SCHEMBL19209038 0.86 GAA (0.44) PLK1PLK3HDAC2ALDH1A1GAA
SCHEMBL26741098 0.84 SMN1; SMN2 (0.58) ALDH1A1GAATAS1R3TAS1R1SMN1; SMN2
SCHEMBL26741094 0.84 SMN1; SMN2 (0.58) ALDH1A1GAATAS1R3TAS1R1SMN1; SMN2
SCHEMBL17892684 0.79 PLK1 (0.46) PLK1PLK3ALDH1A1GAAPTPN1
SCHEMBL17892683 0.79 PLK1 (0.46) PLK1PLK3ALDH1A1GAAPTPN1
SCHEMBL23881509 0.77 HDAC2 (0.36) HDAC2LMNANPC1RAB9APOLB
SCHEMBL30089260 0.77 HDAC2 (0.36) HDAC2LMNANPC1RAB9APOLB
SCHEMBL23881511 0.77 HDAC2 (0.36) HDAC2LMNANPC1RAB9APOLB
SCHEMBL6996812 0.76 PLK1 (0.51) PLK1PLK3ALDH1A1PTPN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104262344-B The preparation method of Chinese mugwort Dana Delany SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) 2015-11-04 CN claimed