Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209037 | 1.00 | GAA (0.44) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19576325 | 0.86 | KMT2A (0.49) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19935743 | 0.86 | KMT2A (0.49) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL28043044 | 0.86 | PLK1 (0.49) | GAARAB9ALMNAALDH1A1PLK1 | |
| SCHEMBL28499579 | 0.85 | KCNQ2 (0.48) | GAAJAK2JAK1TYK2MEN1 | |
| SCHEMBL16583355 | 0.83 | MEN1 (0.44) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19576319 | 0.83 | GAA (0.43) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL26741098 | 0.81 | SMN1; SMN2 (0.58) | GAAHTTMEN1KMT2ARAB9A | |
| SCHEMBL26741094 | 0.81 | SMN1; SMN2 (0.58) | GAAHTTMEN1KMT2ARAB9A | |
| SCHEMBL16345869 | 0.81 | GAA (0.48) | GAAJAK2JAK1TYK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190040066-A1 | PROCESS FOR THE PREPARATION OF PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | LUPIN LIMITED (IN) | 2019-02-07 | — | — | US | disclosed |
| EP-3411376-A1 | A PROCESS FOR THE PREPARATION OF PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | Lupin Limited (IN) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017134607-A1 | A PROCESS FOR THE PREPARATION OF PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | LUPIN LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040066-A1 | PROCESS FOR THE PREPARATION OF PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | PIK3CA, PIK3C2B, PIK3CD | GAA 1160/4885JAK2 433/4885JAK1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.