Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804304 | 1.00 | KDM4E (0.58) | KDM4EMAPTGAACASP3GFER | |
| SCHEMBL18021074 | 0.83 | KDM4E (0.58) | KDM4EMAPTGAACA12CA2 | |
| SCHEMBL16710523 | 0.81 | KDM4E (0.56) | KDM4EMAPTGAACA12CA2 | |
| SCHEMBL13310281 | 0.79 | KDM4E (0.54) | KDM4EMAPTGAACA12CA2 | |
| SCHEMBL6841042 | 0.78 | PARP1 (0.50) | KDM4EMAPTCASP3GFERSENP8 | |
| SCHEMBL30620493 | 0.78 | PARP1 (0.50) | KDM4EMAPTCASP3GFERSENP8 | |
| SCHEMBL8407427 | 0.78 | PARP1 (0.50) | KDM4EMAPTCASP3GFERSENP8 | |
| SCHEMBL13128199 | 0.78 | KDM4E (0.53) | KDM4EMAPTGAACA12CA2 | |
| SCHEMBL10281920 | 0.78 | KDM4E (0.67) | KDM4EMAPTGAACA12CA2 | |
| SCHEMBL16683714 | 0.78 | KDM4E (0.53) | KDM4EMAPTGAACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108355709-B | Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst | 嘉兴学院 | 2020-12-08 | — | — | CN | claimed |
| US-20080255383-A1 | PREPARATION OF RIVASTIGMINE AND ITS SALTS | DR. REDDY'S LABORATORIES, INC. | 2008-10-16 | — | — | US | claimed |
| CN-108355709-B | Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst | 嘉兴学院 | 2020-12-08 | — | — | CN | disclosed |
| CN-108355709-A | Purposes of the Bismuth triflate as Beckmann rearrangement catalyst | 嘉兴学院 | 2018-08-03 | — | — | CN | disclosed |
| US-9725423-B2 | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| WO-2014084223-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2014-06-05 | — | — | WO | disclosed |
| US-20130296327-A1 | SUBSTITUTED HETEROCYLIC COMPOUNDS | INCYTE CORPORATION | 2013-11-07 | — | — | US | disclosed |
| US-8481732-B2 | Substituted heterocyclic compounds | INCYTE CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-20100240671-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | INCYTE CORPORATION (US) | 2010-09-23 | — | — | US | disclosed |
| WO-2010108059-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS ANTAGONISTS OF THE HISTAMINE H4 RECEPTOR | INCYTE CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
| EP-0934283-A2 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0929570-A1 | MODIFIED CYTOSTATIC AGENTS | BAYER AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998015571-A1 | MODIFIED CYTOSTATIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998005652-A2 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296327-A1 | SUBSTITUTED HETEROCYLIC COMPOUNDS | HRH4, HRH2, HRH1 | KDM4E 1238/4885MAPT 3212/4885GAA 3135/4885 |
| US-20100240671-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | HRH4, HRH2, HRH1 | KDM4E 972/4885MAPT 2968/4885GAA 2165/4885 |
| US-20080255383-A1 | PREPARATION OF RIVASTIGMINE AND ITS SALTS | ACHE, EHMT1, BCHE | KDM4E 23/4885MAPT 1060/4885GAA 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.