Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16008025 | 0.99 | AR (0.46) | ARMAPTALDH1A1MAPK1PRKCZ | |
| SCHEMBL28043446 | 0.84 | NPC1 (0.51) | MAPTBRD4MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL16008341 | 0.83 | MAPT (0.50) | MAPTALDH1A1BRD4MEN1KMT2A | |
| SCHEMBL28873495 | 0.74 | SMN1; SMN2 (0.56) | ARMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL16042754 | 0.72 | BRD4 (0.71) | MAPTALDH1A1MAPK1BRD4MEN1 | |
| Hydrochloric Acid SCHEMBL11463651 | 0.71 | MAPT (0.53) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15069474 | 0.71 | BRD4 (0.76) | BRD4 | |
| SCHEMBL16007874 | 0.70 | SMN1; SMN2 (0.51) | MAPTALDH1A1BRD4MEN1KMT2A | |
| SCHEMBL15069331 | 0.70 | BRD4 (0.77) | BRD4ELANE | |
| SCHEMBL15328848 | 0.69 | BRD4 (0.72) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164127-A | Bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |