Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GALK1 | P51570 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 12/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16008341 | 0.99 | MAPT (0.50) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16007874 | 0.85 | SMN1; SMN2 (0.51) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL28043101 | 0.84 | AR (0.47) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL16008025 | 0.83 | AR (0.46) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11463651 | 0.79 | MAPT (0.53) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16008399 | 0.74 | BRD4 (0.59) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16008336 | 0.74 | BRD4 (0.72) | NPC1MAPTSMN1; SMN2LMNABRD4 | |
| SCHEMBL25194957 | 0.73 | CA12 (0.56) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16008102 | 0.73 | BRD4 (0.59) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL538560 | 0.72 | SMN1; SMN2 (0.68) | MAPTSMN1; SMN2LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164127-A | Bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |