Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367319 | 0.75 | MAPT (0.51) | MAPTKDM4E | |
| SCHEMBL31082541 | 0.74 | MAPK1 (0.42) | MAPTKDM4EPOLBHTTLMNA | |
| SCHEMBL28116240 | 0.71 | CYP19A1 (0.44) | MAPTKDM4ELMNA | |
| SCHEMBL4249660 | 0.70 | DHPS (0.57) | KDM4EHTTLMNASTING1HTR1A | |
| SCHEMBL4383990 | 0.69 | CYP1A2 (0.39) | MAPTKDM4EPOLBHTTRAD52 | |
| SCHEMBL28001902 | 0.68 | STING1 (0.38) | MAPTKDM4EPOLBHTTRAD52 | |
| SCHEMBL29720794 | 0.68 | BRD9 (0.44) | MAPTSTING1HTR1AHTR2ADRD2 | |
| SCHEMBL15344922 | 0.68 | BRD9 (0.44) | MAPTSTING1HTR1AHTR2ADRD2 | |
| SCHEMBL30171226 | 0.68 | HTR2A (0.38) | MAPTSTING1HTR1AHTR2AIDO1 | |
| SCHEMBL28948256 | 0.68 | HTR2A (0.38) | MAPTSTING1HTR1AHTR2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153156-A | Preparation method for 4-phenyl-2,7-naphthyridine-1(2H)-ketone | XU FENG | 2015-12-16 | — | — | CN | disclosed |