Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289211 | 1.00 | PARP1 (0.44) | PARP1ALDH1A1SMN1; SMN2HSD17B10CTSK | |
| SCHEMBL8315451 | 0.84 | PARP1 (0.41) | PARP1ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28094553 | 0.84 | PARP1 (0.44) | PARP1SMN1; SMN2HSD17B10USP2HPGD | |
| SCHEMBL28135174 | 0.84 | PARP1 (0.44) | PARP1SMN1; SMN2HSD17B10USP2HPGD | |
| SCHEMBL27722775 | 0.81 | PARP1 (0.45) | PARP1SMN1; SMN2HSD17B10USP2HPGD | |
| SCHEMBL27717164 | 0.81 | PARP1 (0.45) | PARP1SMN1; SMN2HSD17B10USP2HPGD | |
| SCHEMBL336578 | 0.79 | PARP1 (0.54) | PARP1ALDH1A1SMN1; SMN2HSD17B10CTSK | |
| SCHEMBL337351 | 0.79 | PARP1 (0.54) | PARP1ALDH1A1SMN1; SMN2HSD17B10CTSK | |
| SCHEMBL336577 | 0.79 | PARP1 (0.54) | PARP1ALDH1A1SMN1; SMN2HSD17B10CTSK | |
| SCHEMBL18789978 | 0.79 | PARP1 (0.41) | PARP1ALDH1A1SMN1; SMN2HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674254-B | Quinolone carboxylic acid compounds and intermediates, preparation method and application thereof | 广东省中医院 | 2019-03-15 | — | — | CN | claimed |
| CN-106674254-B | Quinolone carboxylic acid compounds and intermediates, preparation method and application thereof | 广东省中医院 | 2019-03-15 | — | — | CN | disclosed |
| CN-109251211-A | A kind of quinolonecarboxylic acid compound and its intermediate, preparation method and application | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2019-01-22 | — | — | CN | disclosed |
| CN-105188705-A | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | UNIV MICHIGAN | 2015-12-23 | — | — | CN | disclosed |