Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083393 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9083377 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12709974 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL31509357 | 0.82 | MAPT (0.56) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1360146 | 0.82 | MAPT (0.56) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9080448 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL547498 | 0.81 | KMT2A (0.51) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20065126 | 0.81 | KMT2A (0.51) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3109240 | 0.81 | MEN1 (0.48) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16115687 | 0.79 | MAPT (0.51) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164122-A | Substituted oxopyridine derivatives and their use in the treatment of cardiovascular disorders | Bayer Pharma AG | 2015-12-16 | — | — | CN | disclosed |