Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | S100B | P04271 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975255 | 0.83 | AR (0.56) | ARPDK2 | |
| SCHEMBL2793351 | 0.83 | AR (0.56) | ARPDK2 | |
| SCHEMBL2567623 | 0.83 | AR (0.56) | ARPDK2 | |
| SCHEMBL2970533 | 0.80 | CCNE2 (0.43) | AR | |
| SCHEMBL2978130 | 0.80 | CCNE2 (0.43) | AR | |
| SCHEMBL2970530 | 0.80 | CCNE2 (0.43) | AR | |
| SCHEMBL2980700 | 0.79 | AR (0.52) | ARPDK2KMT2AMEN1MAPT | |
| SCHEMBL2980699 | 0.79 | AR (0.52) | ARPDK2KMT2AMEN1MAPT | |
| SCHEMBL2978178 | 0.79 | HSD11B1 (0.45) | ARNOTUMKMT2AMAPT | |
| SCHEMBL12709289 | 0.78 | DPP4 (0.39) | ARPDK2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188371-A | Erk inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-23 | — | — | CN | disclosed |