SCHEMBL28043975

SCHEMBL28043975

CCc1ccc(OP(=O)(O)Oc2cc(C)cc(C)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CYP3A4 P08684 3/20 0.47
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 1/20 0.43
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
BLM P54132 1/20 0.39
SRC P12931 1/20 0.38
POLB P06746 1/20 0.38
ABCB1 P08183 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28149403 0.88 CYP2C19 (0.64) CYP2C19SMN1; SMN2CYP3A4TSHRALDH1A1
SCHEMBL2150400 0.88 SMN1; SMN2 (0.72) CYP2C19SMN1; SMN2ALDH1A1TDP1LMNA
SCHEMBL3474625 0.87 CYP3A4 (0.66) CYP2C19SMN1; SMN2CYP3A4TSHRALDH1A1
SCHEMBL11851141 0.85 ALDH1A1 (0.47) CYP2C19SMN1; SMN2CYP3A4TSHRALDH1A1
SCHEMBL11398356 0.82 ALDH1A1 (0.67) SMN1; SMN2CYP3A4TSHRALDH1A1MAPK1
SCHEMBL23501799 0.81 CYP2C19 (0.64) CYP2C19SMN1; SMN2ALDH1A1CES2CES1
Fluoride SCHEMBL31047199 0.80 ALDH1A1 (0.64) SMN1; SMN2CYP3A4TSHRALDH1A1MAPK1
SCHEMBL27637440 0.80 ALDH1A1 (0.53) SMN1; SMN2CYP3A4TSHRALDH1A1MAPK1
SCHEMBL6854005 0.79 TSHR (0.49) CYP2C19SMN1; SMN2CYP3A4TSHRALDH1A1
SCHEMBL1101448 0.77 CYP2C19 (0.72) CYP2C19SMN1; SMN2ALDH1A1BLMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105189604-A Production of a polycarbonate with limited metal residuals SABIC INNOVATIVE PLASTICS IP 2015-12-23 CN disclosed