Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044070 | 0.79 | BRD4 (0.44) | BRD4 | |
| SCHEMBL16045116 | 0.79 | BRD4 (0.46) | BRD4 | |
| SCHEMBL16046578 | 0.79 | BRD4 (0.57) | BRD4 | |
| SCHEMBL16047916 | 0.78 | BRD4 (0.47) | BRD4 | |
| SCHEMBL16045727 | 0.78 | BRD4 (0.75) | BRD4 | |
| SCHEMBL16046716 | 0.76 | BRD4 (0.45) | BRD4 | |
| Ethoxycarbonyl Group SCHEMBL28044113 | 0.76 | HTR1A (0.45) | BRD4 | |
| SCHEMBL16045482 | 0.75 | BRD4 (0.79) | BRD4 | |
| SCHEMBL16045885 | 0.72 | BRD4 (0.76) | BRD4 | |
| SCHEMBL16046533 | 0.69 | BRD4 (0.77) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164130-A | Dihydro-pyrrolopyridone bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | claimed |
| CN-105164130-A | Dihydro-pyrrolopyridone bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |