Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23493028 | 1.00 | RIPK1 (0.47) | RIPK1MCHR1ALDH1A1GLABRD4 | |
| SCHEMBL21694263 | 0.92 | RIPK1 (0.46) | RIPK1MCHR1ALDH1A1GLABRD4 | |
| SCHEMBL21694248 | 0.92 | MCHR1 (0.55) | RIPK1MCHR1ALDH1A1GLABRD4 | |
| SCHEMBL21694239 | 0.91 | RIPK1 (0.41) | RIPK1MCHR1ALDH1A1GLABRD4 | |
| SCHEMBL21694175 | 0.90 | RIPK1 (0.43) | RIPK1MCHR1ALDH1A1GLABRD4 | |
| SCHEMBL21694176 | 0.87 | CYP3A4 (0.45) | RIPK1MCHR1ALDH1A1BRD4NOS3 | |
| SCHEMBL21694233 | 0.86 | RIPK1 (0.38) | RIPK1MCHR1BRD4NOS3NOS1 | |
| SCHEMBL21693986 | 0.86 | CBX7 (0.39) | RIPK1MCHR1BRD4NOS3NOS1 | |
| SCHEMBL10503371 | 0.82 | MCHR1 (0.48) | RIPK1MCHR1ALDH1A1HTR2CDHFR | |
| SCHEMBL23493046 | 0.82 | RIPK1 (0.38) | RIPK1MCHR1ALDH1A1GLABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069905-A | A kind of pyrazol acid amide compounds and its application | 沈阳中化农药化工研发有限公司 | 2018-05-25 | — | — | CN | disclosed |
| CN-108059613-A | A kind of pyrazol acid amide compounds and application | 沈阳中化农药化工研发有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-105164130-A | Dihydro-pyrrolopyridone bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |