Phosphine

Phosphine

SCHEMBL28044192

CCC(CC(=O)O)C(=O)O.P.[AlH3]

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.50
CA2 P00918 1/20 0.48
MAPK1 P28482 1/20 0.48
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
CHRM1 P11229 1/20 0.44
AKR1A1 P14550 1/20 0.44
CHRM3 P20309 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
ADRA1A P35348 1/20 0.44
HRH1 P35367 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
CPA1 P15085 2/20 0.42
CPB1 P15086 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26838933 0.95 FOLH1 (0.54) FOLH1CA2MAPK1SLC1A3SLC1A2
SCHEMBL61510 0.95 FOLH1 (0.54) FOLH1CA2MAPK1SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL4145272 0.92 FOLH1 (0.52) FOLH1CA2MAPK1SLC1A3SLC1A2
SCHEMBL28011342 0.92 FOLH1 (0.52) FOLH1CA2MAPK1SLC1A3SLC1A2
Ammonia Solution, Strong SCHEMBL9400233 0.92 FOLH1 (0.52) FOLH1CA2MAPK1SLC1A3SLC1A2
Water SCHEMBL15665821 0.92 FOLH1 (0.52) FOLH1CA2MAPK1SLC1A3SLC1A2
Ammonia Solution, Strong SCHEMBL28859153 0.92 FOLH1 (0.52) FOLH1CA2MAPK1SLC1A3SLC1A2
Methylene Chloride SCHEMBL7435842 0.88 FOLH1 (0.48) FOLH1CA2MAPK1SLC1A3SLC1A2
Glycine SCHEMBL2323603 0.86 SLC1A3 (0.48) FOLH1CA2MAPK1SLC1A3SLC1A2
Hexane SCHEMBL7254732 0.86 CA2 (0.61) FOLH1CA2MAPK1SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105104456-A Preparation method of verticillium dahliae resistant composition JIANG XIANHUI 2015-12-02 CN disclosed