Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033896 | 0.89 | TSHR (0.42) | TSHRHCAR2HPGDALDH1A1TP53 | |
| SCHEMBL9736427 | 0.89 | TSHR (0.42) | TSHRHCAR2HPGDALDH1A1TP53 | |
| SCHEMBL22230402 | 0.89 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL22129735 | 0.86 | TSHR (0.39) | TSHRHCAR2HPGDALDH1A1 | |
| SCHEMBL1774088 | 0.84 | TSHR (0.38) | TSHRHCAR2HPGDALDH1A1 | |
| SCHEMBL2884185 | 0.82 | TSHR (0.37) | TSHRHCAR2 | |
| SCHEMBL28020538 | 0.82 | TSHR (0.37) | TSHRHCAR2ALDH1A1 | |
| SCHEMBL23494140 | 0.82 | TSHR (0.34) | TSHR | |
| SCHEMBL1356686 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL20083026 | 0.79 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104023976-B | Duplexer and uses thereof | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |