Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14851130 | 0.88 | PSMB5 (0.67) | TTRAKR1C3ALDH1A1CYP2C9NPSR1 | |
| SCHEMBL27687370 | 0.84 | ALPI (0.53) | ALDH1A1MAPTKDM4ECAPN1SMN1; SMN2 | |
| SCHEMBL27687371 | 0.84 | ALPI (0.53) | ALDH1A1MAPTKDM4ECAPN1SMN1; SMN2 | |
| SCHEMBL14851131 | 0.83 | APP (0.64) | TTRALDH1A1CYP2C9NPSR1TSHR | |
| SCHEMBL28020206 | 0.81 | CAPN1 (0.47) | ALDH1A1NPSR1MAPTCAPN1 | |
| SCHEMBL28051509 | 0.80 | ALDH1A1 (0.60) | TTRALDH1A1TSHRPSMB5MAPT | |
| SCHEMBL20719975 | 0.80 | AKR1C3 (0.76) | TTRAKR1C3ALDH1A1HPGD | |
| SCHEMBL23631861 | 0.80 | ALDH1A1 (0.56) | TTRAKR1C3ALDH1A1CYP2C9NPC1 | |
| SCHEMBL28490352 | 0.79 | PPARA (0.54) | TTRALDH1A1CYP2C9NPC1RAB9A | |
| SCHEMBL29126022 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP2C9NPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283547-A | Recombinant host cell for biosynthetic production | RHODIA OPERATIONS | 2016-01-27 | — | — | CN | disclosed |