Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 11/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | SPAST | Q9UBP0 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259555 | 1.00 | RAD52 (0.43) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL27768783 | 0.82 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL17884678 | 0.80 | SLC6A2 (0.57) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL17884836 | 0.80 | SLC6A2 (0.57) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL1028438 | 0.80 | SLC6A2 (0.57) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| Bromide SCHEMBL10498794 | 0.80 | RAD52 (0.45) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL3614369 | 0.79 | SLC18A3 (0.34) | — | |
| Bromide SCHEMBL10498800 | 0.79 | SLC6A2 (0.55) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL21340093 | 0.79 | SLC6A2 (0.55) | RAD52SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL21340085 | 0.79 | SLC6A2 (0.55) | RAD52SLC6A2SLC6A4SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073745-A | Glucosylceramide synthase inhibitors | GENZYME CORP | 2015-11-18 | — | — | CN | disclosed |