Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 14/20 | 0.34 |
| ▸ | HTR2B | P41595 | 12/20 | 0.34 |
| ▸ | HTR2A | P28223 | 8/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259555 | 0.82 | RAD52 (0.43) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL28044630 | 0.82 | RAD52 (0.43) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL2454158 | 0.80 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL3603226 | 0.76 | KMT2A (0.32) | — | |
| SCHEMBL3600332 | 0.76 | KMT2A (0.32) | — | |
| SCHEMBL3608911 | 0.76 | KMT2A (0.32) | — | |
| SCHEMBL3612987 | 0.75 | MBTD1 (0.33) | — | |
| SCHEMBL3610379 | 0.75 | MBTD1 (0.33) | — | |
| SCHEMBL3597141 | 0.75 | MBTD1 (0.33) | — | |
| SCHEMBL2182852 | 0.72 | ADRB1 (0.59) | SLC6A4HTR2CHTR2BHTR2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421264-A | Is suitable for treating serotonin 5HT6Heterocyclic compounds for receptor-modulated responsive disorders | ABBOTT GMBH & CO KG (DE) | 2009-04-29 | — | — | CN | disclosed |