SCHEMBL28044647

SCHEMBL28044647

CCc1ccccc1C(O)(C(=O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.52
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HIF1A Q16665 2/20 0.44
CYP2D6 P10635 2/20 0.44
CHRM2 P08172 4/20 0.42
CHRM1 P11229 4/20 0.42
CHRM3 P20309 4/20 0.42
CHRM4 P08173 3/20 0.42
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
POLB P06746 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CYP2C19 P33261 1/20 0.39
CHRM5 P08912 1/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9447535 0.84 CYP2C9 (0.50) CYP2C9LMNAHTTL3MBTL1HIF1A
SCHEMBL8727229 0.83 CYP2C9 (0.42) CYP2C9LMNAHTTL3MBTL1HIF1A
SCHEMBL5709851 0.83 BID (0.47)
SCHEMBL6924319 0.82 CYP2C9 (0.42) CYP2C9LMNAL3MBTL1HIF1ACYP2D6
SCHEMBL11014631 0.81 POLB (0.48) LMNAHTTL3MBTL1CYP2D6CHRM2
SCHEMBL8134336 0.81 SMN1; SMN2 (0.44) CYP2C9LMNAHIF1ACYP2D6CHRM2
Benzylic Acid SCHEMBL7066 0.80 CYP2C9 (0.74) CYP2C9LMNAHTTL3MBTL1HIF1A
SCHEMBL30335199 0.80 KCNN4 (0.44) HIF1ACYP2D6ALDH1A1KMT2AMAPT
SCHEMBL11567881 0.80 CYP2C9 (0.40) CYP2C9LMNAHTTL3MBTL1HIF1A
SCHEMBL20263105 0.79 GABRA1 (0.45) CYP2C9LMNAHTTL3MBTL1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103613502-B 1,1-phenylbenzene-1-hydroxyl ethyl acetate preparation method WUHAN EASTIN CHEMICAL INDUSTRY CO., LTD. (CN) 2016-01-06 CN disclosed