Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370463 | 0.85 | CHRM2 (0.39) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL6026752 | 0.85 | CHRM2 (0.39) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL6026756 | 0.85 | CHRM2 (0.39) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL13125666 | 0.85 | CHRM2 (0.39) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL974483 | 0.85 | CHRM2 (0.39) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL25347682 | 0.85 | CHRM2 (0.37) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL25349102 | 0.85 | MEN1 (0.36) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL4370286 | 0.80 | RECQL (0.32) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL2956240 | 0.80 | RECQL (0.32) | EPHX1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL2964589 | 0.80 | RECQL (0.32) | EPHX1CHRM2CHRM1CHRM3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073715-A | Dihydropyridazine-3,5-dione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |