Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026756 | 1.00 | CHRM2 (0.39) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL13125666 | 1.00 | CHRM2 (0.39) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL974483 | 1.00 | CHRM2 (0.39) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL4370463 | 1.00 | CHRM2 (0.39) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL28044757 | 0.85 | EPHX1 (0.37) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL28735688 | 0.85 | CHRM2 (0.41) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL29519744 | 0.85 | CHRM2 (0.41) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL25348441 | 0.85 | ALDH1A1 (0.38) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL30782513 | 0.85 | ALDH1A1 (0.38) | CHRM2CHRM1CHRM3EPHX1HPGD | |
| SCHEMBL24069211 | 0.80 | CHRM2 (0.44) | CHRM2CHRM1CHRM3EPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506178-A4 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2006-05-24 | — | — | EP | disclosed |
| EP-1506178-A2 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003096980-A2 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-27 | — | — | WO | disclosed |