SCHEMBL28044827

SCHEMBL28044827

COc1ccc(C[C@@H](C)C(N)C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.65
SLC6A4 P31645 1/20 0.59
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
TPH1 P17752 2/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
ACACB O00763 1/20 0.46
POLB P06746 1/20 0.46
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28044828 1.00 LDHA (0.65) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL11439967 0.83 LDHA (0.63) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL11439969 0.83 LDHA (0.63) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL30963023 0.81 SLC1A3 (0.47) CYP2D6PPARGPPARASLC1A3SLC1A2
SCHEMBL158667 0.81 LDHA (0.71) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL597743 0.81 LDHA (0.71) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL126195 0.81 LDHA (0.71) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL4990742 0.81 LDHA (0.61) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL15835402 0.81 SLC1A3 (0.65) SLC6A4CYP1A2CYP2D6CYP2C19SLC1A3
SCHEMBL2587281 0.81 SLC1A3 (0.65) SLC6A4CYP1A2CYP2D6CYP2C19SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294413-A Method for preparing aldehyde/ketone by catalyzing alcohol oxidation with iron salt UNIV ZHEJIANG TECHNOLOGY 2016-02-03 CN claimed
CN-105294413-A Method for preparing aldehyde/ketone by catalyzing alcohol oxidation with iron salt UNIV ZHEJIANG TECHNOLOGY 2016-02-03 CN disclosed