SCHEMBL28045205

SCHEMBL28045205

CC(=O)OC(C)(O)c1ccccc1.[O-][S+](Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
KMT2A Q03164 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.37
KCNN4 O15554 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 2/20 0.36
ALOX15 P16050 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8324538 0.89 CYP2C19 (0.48) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL11436123 0.76 CYP2C19 (0.50) CYP2C19HIF1AKMT2AMAPTMEN1
SCHEMBL11379208 0.74 CYP2C19 (0.52) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL5326125 0.73 CYP2C19 (0.47) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL11876274 0.72 CYP2C19 (0.43) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL42458 0.72 ALDH1A1 (0.56) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL20972999 0.72 KCNN4 (0.45) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL14878271 0.72 KCNN4 (0.45) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL17468466 0.72 CYP2C19 (0.46) CYP2C19HIF1AKMT2AMAPTMEN1
SCHEMBL1878327 0.71 KCNN4 (0.44) CYP2C19HIF1AKMT2AMAPTKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103360249-B To acetoxyl methyl phenyl carbinol and the preparation method to acetoxystyrene SINOPEC CORP. (CN) 2015-12-02 CN disclosed