Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625144 | 0.79 | KMT2A (0.42) | RAB9AHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7520413 | 0.73 | HDAC6 (0.54) | RAB9AHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21261882 | 0.73 | BRD4 (0.37) | CYP2D6CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL28018812 | 0.70 | EPHX1 (0.49) | EPHX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11172803 | 0.69 | EPHX1 (0.50) | RAB9AHPGDEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL21261872 | 0.67 | CYP2D6 (0.40) | CYP2D6RAB9AHPGDEPHX1SMN1; SMN2 | |
| SCHEMBL11533429 | 0.67 | CYP2C9 (0.65) | CYP2D6CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL6946769 | 0.67 | POLB (0.42) | TSHRHPGDALDH1A1KMT2AMAPT | |
| SCHEMBL6928359 | 0.67 | POLB (0.42) | TSHRHPGDALDH1A1KMT2AMAPT | |
| SCHEMBL827636 | 0.67 | POLB (0.42) | TSHRHPGDALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105307667-A | Stapled and sutured polypeptides and uses thereof | HARVARD COLLEGE | 2016-02-03 | — | — | CN | disclosed |