Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602062 | 0.93 | CYP2C9 (0.59) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL258716 | 0.91 | CYP2C9 (0.62) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL3662909 | 0.91 | SMN1; SMN2 (0.71) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL376127 | 0.91 | CYP1A2 (0.57) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL3457884 | 0.91 | TSHR (0.57) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL27866 | 0.90 | CYP2D6 (0.80) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL1694370 | 0.89 | L3MBTL1 (0.62) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL12466491 | 0.89 | CYP1A2 (0.55) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL3278767 | 0.89 | CYP2C9 (0.55) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR | |
| SCHEMBL5166934 | 0.89 | CYP1A2 (0.55) | CYP2C9CYP2C19CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |