SCHEMBL28045328

SCHEMBL28045328

Cc1cc(C)cc(CCCCC(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
F13A1 P00488 3/20 0.50
FABP4 P15090 1/20 0.49
HDAC3 O15379 1/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48
HDAC4 P56524 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HDAC1 Q13547 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
FFAR1 O14842 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22190396 0.94 MAPK1 (0.55) MAPTRXFP1F13A1FABP4HDAC3
SCHEMBL5846204 0.85 FFAR1 (0.61) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL27755047 0.84 PARP10 (0.40) MAPTRXFP1HDAC3HDAC4HDAC1
SCHEMBL3249491 0.82 MAPT (0.62) MAPTRXFP1HDAC3MAPK1ADRA1A
SCHEMBL8357921 0.81 MAPT (0.52) MAPTRXFP1F13A1FABP4HDAC3
SCHEMBL9663089 0.80 MAPT (0.66) MAPTRXFP1HDAC3MAPK1ADRA1A
SCHEMBL765851 0.80 MAPT (0.66) MAPTRXFP1HDAC3MAPK1ADRA1A
SCHEMBL713464 0.80 MAPT (0.66) MAPTRXFP1HDAC3MAPK1ADRA1A
SCHEMBL29057552 0.80 MAPT (0.66) MAPTRXFP1HDAC3MAPK1ADRA1A
SCHEMBL1066202 0.80 MAPT (0.66) MAPTRXFP1HDAC3MAPK1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171516-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2025-05-29 US disclosed
WO-2025096921-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2025-05-08 WO disclosed
CN-116615251-A Antibody-drug conjugates comprising GLP1 peptide mimetics and the uses thereof 瑞泽恩制药公司 2023-08-18 CN disclosed
CN-106414434-A Isothiazole derivatives as gpr120 agonists for the treatment of type ii diabetes 詹森药业有限公司 2017-02-15 CN disclosed
CN-105209446-A GPR120 agonists for the treatment of type ii diabetes JANSSEN PHARMACEUTICA NV 2015-12-30 CN disclosed
CN-105209444-A Benzo-fused heterocyclic derivatives useful as agonists of GPR120 JANSSEN PHARMACEUTICA NV 2015-12-30 CN disclosed
CN-105008345-A BICYCLIC PYRROLE DERIVATIVES USEFUL AS AGONISTS OF GPR120 JANSSEN PHARMACEUTICA NV 2015-10-28 CN disclosed
CN-101068783-A Processes and intermediates for preparing cysteine protease inhibitors BAYER SCHERING PHARMA AG (DE) 2007-11-07 CN disclosed
CN-1809530-A Haloalkyl containing compounds as cysteine protease inhibitors AXYS PHARM INC (US) 2006-07-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171516-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF GLP1R, GIPR, GCGR MAPT 2772/4885RXFP1 32/4885F13A1 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.